shows that it takes 14 minutes for a chewed soluble tablet to produce
maximal platelet inhibition, and a swallowed tablet 26 minutes.
Demonstrating that, when chewed, soluble aspirin is the most effective
way of accelerating absorption of aspirin into the blood and shortening
the time required for an anti-platelet effect, the anti-platelet effect
stops an existing clot from worsening. However, there are several
issues connected with carrying soluble aspirin in pockets, bags or
- During a suspected heart attack the patient may be unable to locate the aspirin.
- If located, the patient may be unable to open the aspirin foil.
the patient was unable to administer the aspirin themselves, it would
not be apparent to a ‘first aider’, that aspirin was being carried and
should be taken as a matter of urgency.
- Aspirin is
extremely susceptible to dampness; this will cause it to lose its
stability, become less effective, and may smell of vinegar.
is particularly prone to break into smaller particles (friability), and
is likely to be powdered when needed and therefore difficult to take.